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Independent Research · Knoxville, Tennessee

A small lab building measurement systems that work.

Artifact Zero Labs develops deterministic measurement systems — for medical imaging, for cryptography, and for problems where the current state of the art is a confident guess. We validate everything we build against ground truth, at population scale, before we put a name on it.

01What we work on
Imaging Medical imaging

Can a single algorithm measure anatomy with subpixel precision across every scanner, every institution, without training data?

We've built one. It recovers anatomical position in one deterministic operation per slice — no thresholds, no per-scanner tuning, no labeled training set. It is a measurement, calibrated against the physics of the acquisition, not against expectations of what it will see.

Validated on cervical spine and brain, against radiologist-read truth on real clinical cases, and at population scale on 582 healthy adults across three institutions and three pulse sequences. The same architectural pattern produces both anatomies. It extends.

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C5 Cryptographic certification

Can cryptographic parameters be certified without trusting the auditor?

C5 takes the RSA key sizes, elliptic curves, or Diffie-Hellman groups a customer already holds, assesses their security against mathematical bounds, and issues a signed certificate. Designed for compliance teams, auditors, and key-policy review where the output needs to be checkable, not just stated.

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AZL Prime generation & verification

What if you don't have the cryptographic infrastructure to begin with?

AZL is a supplier, not just an auditor. It generates certified primes of any requested bit length, verifies primality on integers a customer already holds, and assesses cryptographic parameters across RSA, ECC, and Diffie-Hellman. For teams that need the math done — not just stamped.

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02News
May 2026
Population validation milestone. Brain analyzer run on 582 healthy adult subjects from the IXI public dataset, spanning three imaging centers and three pulse sequences. 1,746 analyses. Median midline shift across the cohort: ±0.04 mm of zero.
Feb 2026
Cross-scanner reproducibility. Cervical spine measurement reproduced on a single patient across three scanners and two institutions, 21 months apart. Findings tracked radiologist-read truth at all time points.
Jan 2026
False-positive correction. A normal brain MRI previously read by a legacy algorithm as 63 mm of midline shift — a clinically impossible result — was correctly read by the new system as zero. Detection confirmed on 31 of 31 slices.
03About the lab

Artifact Zero Labs is an independent research lab in Knoxville, Tennessee. We build measurement systems and validate them rigorously — against ground truth on real cases, at population scale on public reference datasets — before naming them as products.

We are a small group. We do not run a sales organization. The technology we develop is intended for partners with the engineering, regulatory, and commercial infrastructure to deploy it: OEMs, licensees, and operators in the domains where the work applies.

Other programs exist beyond what is described here. The right next step is usually a conversation. Send a note via the contact page.